Adipokine FABP4 integrates energy stores and counterregulatory metabolic responses
نویسندگان
چکیده
منابع مشابه
Adipokine Profiles and Metabolic Health
The epidemic of obesity is a major health problem that leads to medical and socioeconomic burdens on society. Although body mass index (BMI) has been the most commonly used measure to determine the degree of obesity, it does not necessarily reflect the degree of adiposity. Recent observations show that some subpopulations exhibit unexpected metabolic profiles that deviate from the typical dose-...
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The risk of hypoglycemia is one of the major obstacles in the optimum treatment in both type 1 (1,2) and type 2 (3) diabetes, as well as in patients in intensive care units (4). Furthermore, in addition to short-term risks, including death, hypoglycemia also produces long-term health consequences including a substantial risk of death from cardiovascular events (5). Thus therapies to minimize th...
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Metabolic syndrome (MetS) as a collection of obesity-associated disorders is associated with inflammation, oxidative stress, pro-thrombotic state, elevated risk of developing cardiovascular disease and type 2 diabetes. Adiponectin is one of the most abundant peptide hormones derived from adipose tissue. This protein plays a major role in glucose and lipid metabolism and prevents development of ...
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OBJECTIVE To evaluate the time course of leptin, adiponectin, and resting energy expenditure (REE) responses in overweight elderly males after acute resistance exercise protocols of various intensity configurations. RESEARCH DESIGN AND METHODS Forty inactive men (65-82 years) were randomly assigned to one of four groups (n = 10/group): control, low-intensity resistance exercise, moderate-inte...
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Hypoglycemia or glucoprivation triggers protective hormonal counterregulatory and feeding responses to aid the restoration of normoglycemia. Increasing evidence suggests pertinent roles for the brain in sensing glucoprivation and mediating counterregulation, however, the precise nature of the metabolic signals and molecular mediators linking central glucose sensing to effector functions are not...
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ژورنال
عنوان ژورنال: Journal of Lipid Research
سال: 2019
ISSN: 0022-2275
DOI: 10.1194/jlr.s091793